CCR Milestones - Highlights 2016-2017

Contents

Molecular Analysis: Charting the Genetics of Papillary Renal Cell Carcinoma

X-ray Crystallography: Molecular Freeze Frame

01 Director’s Note

12

24

Cryo-electron Microscopy: Sharper Images, Better Drugs

BRCA1 and BRCA2 Genes: Faulty Repair Systems Imaging-based Screening: Explaining Accelerated Aging

MRI-Ultrasound Fusion- guided Procedures: Seeing Prostate Cancer More Clearly

02

14

26

Anticancer Defense: Excess Fats Give Developing Liver Tumors a Chance to Grow

28 New

04

16

Faculty

Gene Regulators: A FOX with No Footprints?

18 The Immune System’s Anticancer Defense: Overcoming the Elements

30

06

Awards & Honors

The Skin Microbiome: Enduring Communities

20 BET Inhibitors: BETting on BRD4

08

Topoisomerases: Managing DNA’s Topology to Keep Genes Active

22 Proteasomes: Marked for Destruction

10